FAN, Xiaodan 樊曉丹

Position Professor
Email xfan - _ -
ORCiD 0000-0002-2744-9030
Phone Number 3943 7930
Fax Number 2603 5188
Address LSB 107

Academic Background

Ph.D. in Statistics (Harvard University)

M.S. in Pattern Recognition & Intelligent Systems (Tsinghua University)

B.E. in Automation (Tsinghua University)

Research Interest

Selected Publications

In Journals:

In Conferences:

In Reivew:

  • Shanjun Mao, Xiaodan Fan (joint corresponding author) and Jie Hu (joint corresponding author). Correlation for Tree-Shaped Datasets and Its Bayesian Estimation. Submitted.
  • Cong Huang, Nianwan Yang, Shuping Wang, Xiaodan Fan, Cong Pian, Jiapeng Luo, Xi Li, Kun Lang, Longsheng Xing, Mingxing Jiang, Wanxue Liu, Wanqiang Qian, Daniel Simberloff, Fanghao Wan, Fei Li. Predicting Insect Invasiveness with Whole-Genome Sequencing Data. Submitted
  • Hangjin Jiang and Xiaodan Fan (corresponding author). The Two-step Clustering Approach for Learning Metastable States from Molecular Dynamics Data. Submitted.
  • Hangjin Jiang, Xuhui Huang, Han Li, Wing Hung Wong, Xiaodan Fan (joint corresponding author). CAPT: A New Method for Revealing Free Energy Landscape from MD data. Submitted.
  • Chaojie Wang, Jin Du and Xiaodan Fan (corresponding author). High-Dimensional Correlation Matrix Estimation for General Continuous Data with Bagging Technique. Submitted.
  • Jie Hu, Zirui Chen, Wenwei Lin and Xiaodan Fan (corresponding author). Bayesian Detection of Event Spreading Pattern from Multivariate Binary Time Series. Submitted.
  • Seungyeul Yoo, Quan Chen, Li Wang, Wenhui Wang, Ankur Chakravarthy, Rita Busuttil, Alex Boussioutas, Dan Liu, Junjun She, Tim R. Fenton, Jiangwen Zhang, Xiaodan Fan, Suet-Yi Leung, Jun Zhu. Molecular and cellular heterogeneity of gastric cancer explained by methylation-driven key regulators. Submitted. DOI: 10.1101/2020.01.27.920744.
  • Cong Pian, Kun Lang, Guangle Zhang, Fei Li (joint corresponding author) and Xiaodan Fan (joint corresponding author). MM-4mCPred: Markov Model for DNA N4-methylcytosine Site Prediction in Six Species. Submitted. (Web Server: MM-4mCPred)

Professional Services

  • Associate Editor, Journal of Computational and Graphical Statistics (2012-07 to Present)
  • Editorial Board Member, Frontiers in Bioinformatics and Computational Biology (2015-04 to Present)
  • Guest Editor, IEEE/ACM Transactions on Computational Biology and Bioinformatics (2014-11 to 2018-04)
  • Referee for Journals: Journal of the American Statistical Association, Annals of Applied Statistics, Journal of Computational and Graphical Statistics, Journal of Statistical Computation and Simulation, Computational Statistics and Data Analysis, IEEE/ACM Trans. on Computational Biology; Bioinformatics, Psychometrika, Technometrics, IEEE Transactions on Signal Processing, PLoS Computational Biology, PLoS One, BMC Bioinformatics, Scientific Reports, etc.
  • Organizing Committee Member of Conferences: the 4th Institute of Mathematical Statistics Asia Pacific Rim Meeting, CUHK Symposium on Statistics, etc.
  • Programme Committee Member of Conferences: ICBBB, ITQM, BIBE, ChinaSIP of IEEE, IDASB of BIBM, etc.


  • STAT 3004: Basic Methods in Biomedical Statistics (undergraduate course)
  • STAT 3011: Workshop on Data Analysis and Statistical Computing (undergraduate course)
  • STAT 6040: Studies on Selected Topics II (postgraduate course)
  • STAT 6106: Applied Bayesian Methods (postgraduate course)

My Graduate Students

Ph.D. Students:

  • Li, Dongrong (Major: Statistics, 2020-present )
  • Zhu, Bencong (Major: Statistics, 2020-present )
  • Liu, Ran (Major: Statistics, 2019-present )
  • Zhang, Zhen (Major: Statistics, 2019-present )
  • Wang, Lijun (Major: Statistics, 2018-present )
  • Lian, Sheng (Major: Statistics, 2017-2021 )
  • Mao, Shanjun (Major: Statistics, 2017-2020)
  • Zhu, Yulin (Major: Statistics, 2016-2020)
  • Jiang, Hangjin (Major: Statistics, 2015-2018)
  • Wang, Chaojie (Major: Statistics, 2014-2018)
  • Shen, Linghao (Major: Information Engineering, 2013-2017)
  • Hu, Jie (Major: Statistics, 2011-2015)
  • Li, Chun (Major: Statistics, 2011-2014)
  • Li, Han (Major: Statistics, 2010-2014)
  • Jiang, Guozhi (Major: Medical Sciences, co-supervised with Prof. Ronald C.W. Ma, 2010-2013)
  • Liang, Tong (Major: Information Engineering, co-supervised with Prof. Shuo-Yen Robert Li, 2008-2013)
  • Han, Shengtong (Major: Statistics, 2009-2012)

M.Phil. Students:

  • Kwok, Chin Kiu (Major: Statistics, 2016-2018)
  • Tang, Sheung Ho (Major: Statistics, 2014-2016)
  • Chen, Zirui (Major: Statistics, 2014-2016)
  • Lau, Yuk Fai (Major: Statistics, 2013-2015)
  • Chan, Kwun Cheung (Major: Statistics, 2012-2014)
  • Lu, Jiayi (Major: Statistics, 2011-2013)
  • Fung, Ling Hiu (Major: Statistics, 2010-2012)
  • Li, Qiwei (Major: Information Engineering, co-supervised with Prof. Shuo-Yen Robert Li, 2008-2010)
  • Wong, Ka Wai (Major: Statistics, 2009-2010)

Research Grants

  • RGC-GRF Grant; Capacity: Principal Investigator
    Title: Consistent Model-free Ultra-high Dimensional Variable Selection for Binary Response
    Period: 2020 – 2022
  • RGC-GRF Grant; Capacity: Principal Investigator
    Title: Detection of Differentially Methylated Regions Based on Array or Sequencing Data
    Period: 2018 – 2020
  • RGC-Theme-based Research Scheme; Capacity: Co-Principal Investigator
    Title: Gastric Cancer Genomics and Beyond – Moving from Patient Samples to 3D Organoid Cultures for Integrative Genomics Analysis, Drug Sensitivity Assays, Cell Biological Studies and Animal Models
    Period: 2016 – 2021
  • RGC-GRF Grant; Capacity: Principal Investigator
    Title: Bayesian Integrative Clustering for Combining Vectorial Data and Network Data
    Period: 2016 – 2018
  • RGC-Theme-based Research Scheme; Capacity: Co-Investigator
    Title: An integrated trans-omics approach to diabetic cardio-renal complications: from novel discoveries to personalized medicine
    Period: 2014 – 2018
  • RGC-GRF Grant; Capacity: Principal Investigator
    Title: Bayesian Model-based Clustering of the Conformational Space of Biomolecules
    Period: 2013 – 2016
  • UGC-AoE Grant; Capacity: Co-Investigator
    Title: Institute of Network Coding
    Period: 2010 – 2017
  • RGC-GRF Grant; Capacity: Principal Investigator
    Title: Bayesian Data Integration Approach for Cell-Cycle Gene Network Inference
    Period: 2010 – 2012
  • ITC-ITF; Capacity: Co-Investigator
    Title: Developing a Platform to Deliver Personalized Healthcare Using Genotype-based Risk Algorithms to Predict Diabetes and Diabetic Complications
    Period: 2010 – 2012

Invited Talks

Invited Talks in Conferences/Workshops:

  • 2019-05-29: Statistical Platform for Common Bioinformatics Analyses. Science Faculty Research Day 2019, The Chinese University of Hong Kong, Hong Kong
  • 2019-05-26: An extended Mallows model for ranked data aggregation. The 2019 Hangzhou International Conference on Frontiers of Data Science, organized by the Center for Data Science of Zhejiang University
  • 2018-10-22: Two Problems of Traditional ODE Gene Regulatory Models. The 8th National Conference on Bioinformatics and Systems Biology of China and The 1st (Macao) International Bioinformatics Symposium, organized by Macao University, Macao
  • 2018-07-06: A New Model for Integrating Rank Lists. The Fifth International Biostatistics Symposium, organized by International Biometric Society China and Sun Yat-sen University, China
  • 2018-05-26: Model-based Clustering for Categorical Data with General High Missingness. The Hong Kong Mathematical Society Annual General Meeting 2018, organized by City University of Hong Kong, Hong Kong
  • 2018-05-12: Several Computational Problems in Comparative Methylation Analyses. Quantitative Biology: Model and Inference, organized by Xiamen University, China
  • 2016-10-15: A New Model for Ranked Data Aggregation. Symposium on Intelligent Information Processing (SIIP), organized by Tsinghua University, China
  • 2016-06-30: Pooling partial observations for efficient estimation of the joint distribution. The 4th Institute of Mathematical Statistics Asia Pacific Rim Meeting, organized by Institute of Mathematical Statistics and The Chinese University of Hong Kong, Hong Kong
  • 2016-03-19: An HMM model for the identification of differentially methylated regions. Workshop on Statistical theories, methodologies and applications in high dimensional data analysis and biomedicine, organized by Hong Kong Baptist University, Hong Kong
  • 2015-06-25: Some Thoughts on Probabilistic Data Integration. The Workshop on Youth Statistician Forum: Prospect and Perspective in Statistical Inference and its Application, organized by The AMSS-PolyU JRI and The Hong Kong Polytechnic University
  • 2015-04-19: Model-based inference of protein dynamics based on MD data. The 2015 Joint Statistical Workshop of The Chinese University of Hong Kong and Academia Sinica, organized by The Chinese University of Hong Kong and Academia Sinica
  • 2015-01-22: Bayesian Detection of Gastric Slow Waves from Micro-electrode Data. Workshop Series in Applied Statistics: Statistical Methods in Medical Science, organized by Hang Seng Management College
  • 2014-12-27: Statistical Learning from Large Molecular Dynamics Datasets. Tsinghua-Sanya Workshop on Big Data: Opportunities, Challenges and Innovations, organized by Tsinghua Sanya International Mathematics Forum
  • 2014-12-16: Conformation Clustering based on MD Simulation Data. The Third International Conference on The Interface Between Statistics and Engineering, organized by City University of Hong Kong and Georgia Institute of Technology
  • 2014-06-27: Integrative Clustering for Heterogeneous Data. The Third Joint Biostatistics Symposium, organized by International Biometrical Society-China Region
  • 2013-08-28: Discuss on Statistical Methods in New Frontiers. The 59th World Statistics Congress, Hong Kong
  • 2013-06-16: Elucidation of the energy landscape of biomolecules by model-based clustering. Beijing Computational Science Research Center Workshop on Energy Landscape of Complex System, Beijing, China
  • 2013-05-30: Probabilistic Integrative Clustering. The 1st Chongqing Workshop on Computational and Applied Mathematics (CQWCAM1), Chongqing, China
  • 2013-04-13: Model-based Integration of Heterogeneous Datasets for Clustering. UC Davis Statistical Sciences Symposium 2013: Analysis of Complex and Massive Data, Davis, CA, USA
  • 2012-12-08: Bayesian Approach for Statistical Data Integration. SYSU Guangdong-HK Statistics Symposium, Guangzhou, Guangdong, China
  • 2012-11-10: A Bayesian Approach for Studying Protein Structural Dynamics. The 2012 Annual Conference of Guangdong Association for Applied Statistics, Shenzhen, Guangdong, China
  • 2011-07-17: A Bayesian Clustering Approach for Partitioning the Conformational Space of Biomolecules. The First Wuxi International Statistics Forum, Wuxi, Jiangsu, China
  • 2010-03-27: Multiple Steady States of Gene Networks. ACM-HK Bioinformatics Symposium 2010, HKUST, Hong Kong
  • 2009-06-20: A Bayesian Data Integration Approach for Detecting Periodicity in Cell Cycle Gene Expression Profiles. The 7th International Bioinformatics Workshop. Soochow University, China
  • 2008-12-16: Statistical Data Integration. BGI-CUHK workshop, BGI, Shenzhen, Guangdong, China

Invited Seminar Talks:

  • 2018-10-19: Institute of Space and Earth Information Science, The Chinese University of Hong Kong
  • 2015-10-23: Department of Chemical Pathology, The Chinese University of Hong Kong
  • 2013-03-26: Department of Mathematics, The University of Hong Kong, Hong Kong
  • 2012-11-07: Department of Statistics & Actuarial Science, The University of Hong Kong, Hong Kong
  • 2012-04-17: School of Mathematics and Computational Science, Sun Yat-sen University, Guangzhou, China
  • 2012-03-30: Department of Applied Mathematics, The Hong Kong Polytechnic University, Hong Kong
  • 2011-12-13: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China
  • 2011-12-13: Faculty of Chemical, Environmental & Biological Science & Technology, Dalian University of Technology, China
  • 2011-12-07: School of Mathematical Sciences, Nankai Univeristy, Tianjin, China
  • 2011-12-05: Beijing Engineering Research Center of Intelligent Rehabilitation Engineering, Peking University, Beijing, China
  • 2010-12-10: Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong
  • 2010-04-01: School of Electrical and Electronic Engineering, North China Electric Power University, Beijing, China
  • 2009-11-19: Department of Biology, The Chinese University of Hong Kong
  • 2009-10-08: Department of Manufacturing Engineering and Engineering Management, City University of Hong Kong
  • 2009-07-16: Bioinformatics Division, TNLIST and Automation Department, Tsinghua University, Beijing, China
  • 2009-03-26: Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong
  • 2009-01-21: Bio-X colloquium, The Chinese University of Hong Kong, Hong Kong
  • 2008-10-14: Department of Mathematics, Hong Kong Baptism University
  • 2008-09-16: Journal Club, Department of Biology, The Chinese University of Hong Kong, Hong Kong
  • 2008-08-19: Department of Electronic & Computer Engineering, Hong Kong University of Science and Technology, Hong Kong