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Dr. Xiaodan Fan

 

Title and Position
Assistant Professor
Department of Statistics
the Chinese University of Hong Kong

Academic Background

Ph.D. in Statistics (Harvard University, Advisor: Prof. Jun S Liu)
M.S. in Pattern Recognition & Intelligent Systems (Tsinghua University, Advisor: Prof. Yanda Li)
B.E. in Automation (Tsinghua University)

Research Interests

Statistical Modeling and Computing - Bayesian inference, Monte Carlo method, Markov chain, hierarchical model, HMM, model selection, RJMCMC, meta-analysis

Computational Biology / Bioinformatics - motif discovery, comparative genomics, gene regulatory network, evolutionary and population genetics, microarray data analysis, cell cycle, gene finding

Pattern Recognition - Bayesian network, SVM, neural network, PCA

Other - knowledge modeling, decision support systems, image processing, Internet-based data mining, operations research

Selected Publications

  • Xiaodan Fan, Yuan Yuan, and Jun S. Liu (2010). "The EM Algorithm and the Rise of Computational Biology". Statistical Science, 25(4), 476-491.

  • Xiaodan Fan, Saumyadipta Pyne, and Jun S. Liu (2010). "Bayesian Meta-Analysis for Identifying Periodically Expressed Genes in Fission Yeast Cell Cycle". The Annals of Applied Statistics, 4(2), 988-1013.

  • Qiwei Li, Tong Liang, Shuo-Yen Robert Li, and Xiaodan Fan (2010). "Bayesian Approach for Identifying Short Adjacent Repeats in Multiple Sequences". In Proceedings of the 2010 International Conference on Bioinformatics & Computational Biology, Jul. 2010, pages 255-261, Las Vegas, Nevada, USA.

  • Xiang Wan, Can Yang, Qiang Yang, Hong Xue, Xiaodan Fan, Nelson L. S. Tang, and Weichuan Yu (2010). "BOOST: A Fast Approach to Detecting Gene-Gene Interactions in Genome-wide Case-Control Studies". American Journal of Human Genetics, 87(3), 325-240.

  • Qiwei Li, Tong Liang, Xiaodan Fan, Chunhui Xu, Weichang Yu, and Shuo-Yen Robert Li (2010). "An Automatic Procedure to Search Highly Repetitive Sequences in Genome as Fluorescence in Situ Hybridization Probes and Its Application on Brachypodium Distachyon". In Proceedings of the 2010 IEEE International Conference on Bioinformatics & Biomedicine, Dec. 2010. pages 563-568, Hong Kong.

  • Jin Xu, Qiwei Li, Xiaodan Fan, Victor O. K. Li, and Shuo-Yen Robert Li (2010). "An Evolutionary Monte Carlo Algorithm for Identifying Short Adjacent Repeats in Multiple Sequences". In Proceedings of the 2010 IEEE International Conference on Bioinformatics & Biomedicine, Dec. 2010. pages 643-648, Hong Kong.

  • Xiaodan Fan and Jun S. Liu (2009). "Comment on 'Bayesian Model for Cross-Study Differential Gene Expression' by Scharpf, Tjelmeland, Parmigiani, and Nobel". Journal of the American Statistical Association, 104(488), 1314-1318.

  • Xiaodan Fan, Jun Zhu, Eric E. Schadt, and Jun S. Liu (2007). "Statistical Power of Phylo-HMM for Evolutionarily Conserved Element Detection". BMC Bioinformatics, 8(1), 374.

  • Yingfei Sun, Xiaodan Fan (Joint First Authors), and Yanda Li (2003). "Identifying Splicing Sites in Eukaryotic RNA: Support Vector Machine Approach". Computers in Biology and Medicine, 33(1), 17-29.

  • Xiaodan Fan, Yingfei Sun, and Yanda Li (2003). "Rapid Development of Real-time Control Systems in C++ Based on RTW". Journal of Tsinghua University, 43(7), 895-898.

  • Yingfei Sun, Xiaodan Fan, and Yanda Li (2003). "Secondary Structural Characteristic of Eukaryotic Gene Splicing Sites". Journal of Tsinghua University, 43(3), 393-395.

Submitted Working Papers (partial):

  • Qiwei Li, Xiaodan Fan, Tong Liang, and Shuo-Yen Robert Li (2011). "MCMC Algorithms for Detecting Short Adjacent Repeats in Multiple Sequences".
  • Tong Liang, Xiaodan Fan, Qiwei Li, and Shuo-Yen Robert Li (2011). "Detection of Short Dispersed Tandem Repeats by Reversible Jump Markov Chain Monte Carlo".
  • Qing Zhang, Xiaodan Fan, Samuel SM Sun, and Dianjing Guo (2011). "Redesign of Transcription Regulation Based on a Mixture Model".
  • Heung Man Lee, Yi Sui, Hailu Zhao, Jennifer MT Siu, Richard KW Choy, Xiaodan Fan, Wing-Yee So, Juliana
    CN Chan, Ronald CW Ma (2011). "The Effects of Uninephrectomy and Accompanied ACEI Treatment on Myocardial Gene Expression"
  • Weiqiang Zhou, Hong Yan, Xiaodan Fan and Quan Hao (2010). "Prediction of Protein-protein Interactions Using Alpha Shape Modeling".

Professional Service

  • Reviewer for Annals of Applied Statistics, Journal of Computational and Graphical Statistics, Computational Statistics and Data Analysis, Statistical Applications in Genetics and Molecular Biology, IIE Transactions, Computers and Electrical Engineering, Journal of Biochemistry and Molecular Biology in the Post-Genomic Era
  • Program Committee Member, BIBM2010 Workshop on Integrative Data Analysis in System Biology organized by IEEE, HKBU, and CUHK. 2010. Hong Kong
  • Program Committee Member, The 3rd International Conference on BioMedical Engineering and Informatics (BMEI'10) organized by Yantai University, IEEE, and EMB. 2010, Yantai, China

Teaching

Spring 2011:

  • STAT 3004: Basic Methods in Biomedical Statistics (undergraduate course)
  • GENA 2182: Science and Modern Society (co-taught undergraduate course)
  • BMEG 5790: Bioinformatics (co-taught M.Sc. course)

Fall 2010:

  • STAT 6040: Studies on Selected Topics II - Bayesian Approach for Bioinformatics Problems (postgraduate course)
  • STAT 3210: Statistical Techniques in Life Sciences (undergraduate course)

My Students and Associates

Research Grants

Talks and Presentations

Useful Links

Contact Information

Address:

Department of Statistics
Room 107, Lady Shaw Building
the Chinese University of Hong Kong
Shatin, New Territories, HONG KONG


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