Statistical Modeling and Computing - Bayesian inference, Monte
Carlo method, Markov chain, hierarchical model, HMM, model selection, RJMCMC,
meta-analysis
Computational Biology / Bioinformatics - motif discovery,
comparative genomics, gene regulatory network, evolutionary and population
genetics, microarray data analysis, cell cycle, gene finding
Other - knowledge modeling, decision support systems, image
processing, Internet-based data mining, operations research
Selected Publications
Xiaodan Fan,
Yuan Yuan, and Jun S. Liu (2010). "The EM Algorithm and the Rise of
Computational Biology". Statistical Science, 25(4), 476-491.
Xiaodan Fan,
Saumyadipta Pyne, and Jun S. Liu (2010). "Bayesian Meta-Analysis for
Identifying Periodically Expressed Genes in Fission Yeast Cell Cycle".
The Annals of Applied Statistics, 4(2), 988-1013.
Qiwei Li, Tong
Liang, Shuo-Yen Robert Li, and Xiaodan Fan (2010). "Bayesian Approach
for Identifying Short Adjacent Repeats in Multiple Sequences". In
Proceedings of the 2010 International Conference on Bioinformatics &
Computational Biology, Jul. 2010, pages 255-261, Las Vegas, Nevada, USA.
Xiang Wan, Can
Yang, Qiang Yang, Hong Xue, Xiaodan Fan, Nelson L. S. Tang, and
Weichuan Yu (2010). "BOOST: A Fast Approach to Detecting Gene-Gene
Interactions in Genome-wide Case-Control Studies". American Journal of
Human Genetics, 87(3), 325-240.
Qiwei Li, Tong
Liang, Xiaodan Fan, Chunhui Xu, Weichang Yu, and Shuo-Yen Robert Li
(2010). "An Automatic Procedure to Search Highly Repetitive Sequences in
Genome as Fluorescence in Situ Hybridization Probes and Its Application on
Brachypodium Distachyon". In Proceedings of the 2010 IEEE International
Conference on Bioinformatics & Biomedicine, Dec. 2010. pages 563-568,
Hong Kong.
Jin Xu, Qiwei
Li, Xiaodan Fan, Victor O. K. Li, and Shuo-Yen Robert Li (2010). "An
Evolutionary Monte Carlo Algorithm for Identifying Short Adjacent Repeats in
Multiple Sequences". In Proceedings of the 2010 IEEE International
Conference on Bioinformatics & Biomedicine, Dec. 2010. pages 643-648,
Hong Kong.
Xiaodan Fan
and Jun S. Liu (2009). "Comment on 'Bayesian Model for
Cross-Study Differential Gene Expression' by Scharpf, Tjelmeland, Parmigiani,
and Nobel". Journal of the American Statistical Association,
104(488), 1314-1318.
Xiaodan Fan,
Jun Zhu, Eric E. Schadt, and Jun S. Liu (2007). "Statistical Power of Phylo-HMM
for Evolutionarily Conserved Element Detection". BMC Bioinformatics,
8(1), 374.
Yingfei Sun,
Xiaodan Fan (Joint First Authors), and Yanda Li (2003). "Identifying
Splicing Sites in Eukaryotic RNA: Support Vector Machine Approach".
Computers in Biology and Medicine, 33(1), 17-29.
Xiaodan Fan,
Yingfei Sun, and Yanda Li (2003). "Rapid Development of Real-time Control
Systems in C++ Based on RTW". Journal of Tsinghua University, 43(7),
895-898.
Yingfei Sun,
Xiaodan Fan, and Yanda Li (2003). "Secondary Structural
Characteristic of Eukaryotic Gene Splicing Sites". Journal of Tsinghua
University, 43(3), 393-395.
Submitted Working Papers (partial):
Qiwei Li, Xiaodan Fan,
Tong Liang, and Shuo-Yen Robert Li (2011). "MCMC Algorithms for Detecting
Short Adjacent Repeats in Multiple Sequences".
Tong Liang, Xiaodan Fan,
Qiwei Li, and Shuo-Yen Robert Li (2011). "Detection of Short Dispersed
Tandem Repeats by Reversible Jump Markov Chain Monte Carlo".
Qing Zhang, Xiaodan Fan,
Samuel SM Sun, and Dianjing Guo (2011). "Redesign of Transcription
Regulation Based on a Mixture Model".
Heung Man Lee, Yi Sui, Hailu Zhao, Jennifer
MT Siu, Richard KW Choy, Xiaodan Fan, Wing-Yee So, Juliana
CN Chan, Ronald CW Ma (2011). "The Effects of Uninephrectomy and Accompanied ACEI
Treatment on Myocardial Gene Expression"
Weiqiang Zhou, Hong Yan, Xiaodan Fan
and Quan Hao (2010). "Prediction of Protein-protein Interactions Using Alpha
Shape Modeling".
Professional Service
Reviewer for Annals of Applied Statistics, Journal of Computational and
Graphical Statistics, Computational Statistics and Data Analysis,
Statistical Applications in Genetics and Molecular Biology, IIE
Transactions, Computers and Electrical Engineering,Journal of
Biochemistry and Molecular Biology in the Post-Genomic Era
Program Committee Member, BIBM2010 Workshop on Integrative Data
Analysis in System Biology organized by IEEE, HKBU, and CUHK. 2010. Hong
Kong
Program Committee Member, The 3rd International Conference on
BioMedical Engineering and Informatics (BMEI'10) organized by Yantai
University, IEEE, and EMB. 2010, Yantai, China
Teaching
Spring 2011:
STAT 3004: Basic Methods in Biomedical
Statistics (undergraduate course)
GENA 2182: Science and Modern Society
(co-taught undergraduate course)